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The individualized smoking cessation treatment for dual smokers of cigarette + electronic cigarette based on genotyping: Randomized controlled trial

The individualized smoking cessation treatment for dual smokers of cigarette + electronic cigarette based on genotyping: Randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111503
Enrollment
Unknown
Registered
2025-10-31
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

smoking Cessation

Interventions

Individualized treatment group:Based on the results of genetic testing, calculate the recommended medication, and express the smoking cessation medication to the study participants
Regular treatment group:The medication is determined by the research doctor based on clinical experience

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Currently using both electronic cigarettes and traditional cigarettes; 2.meeting the criteria for tobacco dependence; 3.aged between 18 and 85 years; 4.willing to participate in this study and sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1.only cigarettes or only electronic cigarettes are used; 2.Allergic to tartrate-based nicotine, bupropion hydrochloride, or similar ingredients; 3.Have received other smoking cessation treatments within 30 days; 4.Pregnant or lactating women; 5.Poor basic conditions, suffering from cardiovascular and cerebrovascular diseases, chronic respiratory diseases, diabetes, and other diseases; 6.Those who take more than 3 types of medications; 7.Those with mental illnesses and drug addicts; those with a history of epilepsy; 8.Subjects who, according to the researcher's judgment, suffer from other diseases or mental states that make them unable to meet the research requirements;

Design outcomes

Primary

MeasureTime frame
6-month continuous smoking abstinence rate verified by expired carbon monoxide;

Secondary

MeasureTime frame
Degree of smoking craving;Treatment compliance;Withdrawal symptoms;

Countries

China

Contacts

Public ContactLiu Zhao

China-Japan Friendship Hospital

Lzlzq2004@126.com+86 10 84205425

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026