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Identification of the Susceptible Genes and Mutation of Abnormal Origin of the Left Coronary Artery from the Pulmonary Artery

Identification of the Susceptible Genes and Mutation of Abnormal Origin of the Left Coronary Artery from the Pulmonary Artery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111490
Enrollment
Unknown
Registered
2025-10-31
Start date
2025-11-13
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anomalous origin of the left coronary artery from the pulmonary artery( ALCAPA)

Interventions

Case series:None

Sponsors

Chest Hospital affiliated to Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The anomalous left coronary artery conforms to the diagnostic criteria for ALCAPA as outlined in the "Chinese Expert Consensus on Surgical Treatment of Congenital Heart Disease" (Section XII: Congenital Coronary Artery Anomalies); 2. Presence of chronic myocardial ischemia symptoms, cardiac enlargement, and valvular insufficiency; 3. Requires surgical intervention; 4. Age 18 years or older, with no gender restriction.

Exclusion criteria

Exclusion criteria: 1. Presence of concomitant congenital heart disease; 2. Lack of essential clinical data; 3. Absence of indications for surgical intervention; 4. Age below 18 years.

Design outcomes

Primary

MeasureTime frame
Susceptibility genes and their mutations;—

Secondary

MeasureTime frame
Demographic information;Imaging data;Perioperative biochemical indicators; Type of surgery;—

Countries

China

Contacts

Public ContactLi Wei, Zhang Yangyang

Chest Hospital affiliated to Shanghai Jiaotong University

fuo1126doc@163.com+86 139 1670 3717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026