breast tumor
Conditions
Interventions
Gold Standard:The reference standard for calculating diagnostic accuracy in this study was the final diagnosis for each breast core needle biopsy slide. This was established through an independent rev
Index test:multimodal vision-language model MINDx
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: - All cases that underwent breast core needle biopsy and successfully obtained a final pathological diagnosis in FUSCC. There are no restrictions on external conditions such as age, gender, and type of lesion.
Exclusion criteria
Exclusion criteria: 1. Cases undergoing anti-tumor drug treatment before core needle biopsy, where the purpose of the biopsy is efficacy evaluation; 2. Cases with severely degenerated specimens and insufficient tissue available for diagnosis; 3. Cases with poor quality of specimen sections or scanned images, including the following specific situations: a. Tissue folds or damage accounting for more than 50% of the Region of Interest (ROI) in the section; b. Annotation handwriting or dye covering more than 50% of the ROI area; c. Severely blurred or out-of-focus scanned images that affect the identification of pathological structures.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Macro-F1 Score;Diagnostic Accuracy for Malignant Tumors;Pairwise preference by senior pathologists;Satisfaction score towards the MINDx assistant system;Proportion of cases requiring additional immunohistochemical testing for diagnosis;Average diagnostic time per case; | — |
Primary
| Measure | Time frame |
|---|---|
| Diagnostic Accuracy; | — |
Countries
China
Contacts
Public ContactYang Wentao
Fudan University Shanghai Cancer Center
Outcome results
None listed