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The Effects of Compound Chamomile Lidocaine Gel on Post-Intubation Sore Throat and Inflammatory Response in Children Under General Anesthesia: A Single-Arm Clinical Study

The Effects of Compound Chamomile Lidocaine Gel on Post-Intubation Sore Throat and Inflammatory Response in Children Under General Anesthesia: A Single-Arm Clinical Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111480
Enrollment
Unknown
Registered
2025-10-31
Start date
2025-06-27
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Sore Throat

Interventions

Intervention group:Lubrication treatment of the endotracheal tube: Apply 2-2.5 ml of Compound Chamomile and Lidocaine Gel (STAEDTIGE Arzneimittel GmbH, Germany, 10 g/tube) evenly on the surface of the

Sponsors

Women and Children's Medical Center Affiliated to Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Ages 6 to 18, regardless of gender; 2.Children undergoing elective surgery requiring oral tracheal intubation under general anesthesia; 3.ASA I - II; 4.Expected tracheal tube retention time > 2 hours; 5.Written informed consent was provided by the patient's parents or legal guardians or the patient themselves (>=8 years old).

Exclusion criteria

Exclusion criteria: 1.Patients with oropharyngeal or cervical deformities; 2.Children with a history of difficult airway surgery or expected difficult airway; 3.Patients with a history of respiratory tract disease within the past two weeks and accompanied by any of the following symptoms: sore throat, hoarseness, cough, or expectoration; 4.Children with a history of airway hyperresponsiveness diseases (such as asthma and other wheezing diseases); 5.Patients requiring surgery on the neck, larynx or oropharynx; 6.Patients requiring nasogastric or orogastric tubes; 7.Children requiring postoperative mechanical ventilation; 8.Systemic diseases and coagulation disorders; 9.Children with intellectual disabilities, mental disorders or other reasons that make it difficult to cooperate with the visit; 10.Patients allergic to lidocaine or chamomile-related components; 11.Patients who have participated in other studies within 30 days.

Design outcomes

Primary

MeasureTime frame
Postoperative Sore Throat;

Secondary

MeasureTime frame
Postoperative hoarseness;postoperative cough;Airway reaction after extubation;

Countries

China

Contacts

Public ContactXingrong Song

Women and Children's Medical Center Affiliated to Guangzhou Medical University

sxjess@126.com+86 20 3836 7270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026