Azoospermia
Conditions
Interventions
Azoospermia:None
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1.Patients clinically diagnosed with azoospermia, defined as no sperm detected in semen after standard centrifugation and microscopic examination; 2.Patients who require microsurgical testicular sperm extraction (micro-TESE) according to the routine clinical diagnostic and treatment protocol; 3.After completion of the routine clinical procedures, the remaining testicular biopsy tissue meets the sample requirements for flow cytometry analysis (testicular tissue>= 0.3 cm^3 or >1×10^5 testicular cells); 4.Patients who voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who have received chemotherapy or radiotherapy within the past three months; 2.Patients with uncontrolled infections or tumors of the urogenital system; 3.Patients with severe systemic diseases (e.g., hypertension, diabetes, or hepatic insufficiency) that cannot be controlled by medication; 4.Patients who refuse to provide clinical data or biological samples; 5.Testicular tissue samples that do not meet quality requirements (volume < 0.3 cm^3 or testicular cells < 1×10^5); 6.Any other conditions deemed inappropriate for inclusion by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Results of DNA Ploidy Analysis in Testicular Cells; | — |
Countries
China
Contacts
Public ContactChencheng Yao
Shanghai General Hospital
Outcome results
None listed