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The effect of tramadol on the incidence of nausea and vomiting after gastrointestinal endoscopy under general anesthesia

The effect of tramadol on the incidence of nausea and vomiting after gastrointestinal endoscopy under general anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111433
Enrollment
Unknown
Registered
2025-10-31
Start date
2025-11-03
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Control group:Do not use tramadol

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. men or women aged from 18 to 75; 2. ASA I~III level; 3. Body mass Index (BMI) : 18 to 35kg/m ^2; 4. Patients who are scheduled to undergo gastrointestinal endoscopy under general anesthesia; 5. Clearly understand and voluntarily participate in this research, and sign the informed consent form by oneself.

Exclusion criteria

Exclusion criteria: 1. History of chronic pain or acute pain before surgery, as well as long-term use of painkillers; 2. There were symptoms of nausea and vomiting before the operation or antiemetic drugs were taken; 3. Severe liver and kidney dysfunction; 4. There was a history of depression or anxiety before the operation; 5. Patients with a history of gastrointestinal surgery; 6. Allergic to or contraindicated to the drug components involved in this study; 7. Has participated in other drug clinical trials as a subject within the past three months; 8. Patients who the researchers consider unsuitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative nausea and vomiting ;Sedative and analgesic effects;

Secondary

MeasureTime frame
Postoperative pain score;The incidence of severe postoperative nausea and vomiting;Surgeon satisfaction;

Countries

China

Contacts

Public ContactXie Yegong

Tianjin Medical University General Hospital

xieyegongstudy@sina.com+86 22 6036 1516

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026