Diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients met the 1999 WHO diagnostic criteria for diabetes mellitus. The diagnosis of diabetic kidney disease (DKD) was based on the 2017 Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes, confirming the presence of kidney disease or diabetic nephropathy following the diagnosis of diabetes. Clinical symptoms and signs were consistent with DKD manifestations.
Exclusion criteria
Exclusion criteria: Patients who have experienced severe diabetic complications within the past three months; pregnant or lactating patients; patients with concurrent severe infections, malignant tumors, acute heart failure, or acute stroke.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine Albumin-to-Creatinine Ratio;Estimated Glomerular Filtration Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean amplitude of glucose fluctuation;Mean Amplitude of Glycemic Excursions ;Maximum Blood Glucose Excursion;Average Daily Blood Glucose;Within-day Standard Deviation of Blood Glucose;Fasting Blood Glucose Coefficient of Variation;Time in Range;Serum Uric Acid;Serum Creatinine;Serum Total Bilirubin;Direct Bilirubin ;Indirect Bilirubin ;Alanine Aminotransferase;Aspartate Aminotransferase;Gamma-Glutamyl Transferase;Total Cholesterol;Triglycerides ; Low-Density Lipoprotein Cholesterol;High-Density Lipoprotein Cholesterol ;Apolipoprotein A1;Apolipoprotein B;Fasting Insulin;Fasting Plasma Glucose;Glycated Albumin;Fasting C-Peptide;2-Hour Postprandial C-Peptide ; | — |
Countries
China
Contacts
Affiliated Hospital of Yangzhou University