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Research on the effects and mechanisms of the SUV39H1/FASN signaling pathway on odontogenic differentiation and regenerative function of dental pulp stem cells.

Research on the effects and mechanisms of the SUV39H1/FASN signaling pathway on odontogenic differentiation and regenerative function of dental pulp stem cells.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111384
Enrollment
Unknown
Registered
2025-10-30
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental arch defect

Interventions

Experimental group:Extract dental pulp stem cells

Sponsors

Beijing Stomatological Hospital , Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Ages 12-25, all genders; 2.Tooth extraction treatment is required.

Exclusion criteria

Exclusion criteria: 1.Abnormal tooth development; 2.Dental and periodontal diseases; 3.The periapical film shows abnormal root development. 4.The periapical film shows periapical lesions. 5.Contraindications for tooth extraction; 6.Persons with mental or intellectual disabilities; 7.Women who are menstruating, pregnant, or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Differentiation markers of tooth development (DSPP, DMP1, MEPE, etc.);Key transcription factors (RUNX2, OSX, etc.);—

Countries

China

Contacts

Public ContactXia Dengsheng

Beijing Stomatological Hospital , Capital Medical University

xdsh1202@aliyun.com+86 10 57099110

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026