Suspected prostate cancer
Conditions
Interventions
Intervention Group:Anti-infective therapy
Control group:Placebo
Sponsors
Lishui Central Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.??Age >=18 years old?? ?? ??; 2.Digital rectal examination (DRE) reveals suspicious prostate nodules; 3.??Suspicious lesions detected by transrectal ultrasound (TRUS) or magnetic resonance imaging (MRI)??; 4.??PSA >10 ng/ml; 5.PSA 4–10 ng/ml with abnormal f/t PSA ratio or PSA density (PSAD)??; 6.??Initial prostate biopsy yields negative results??;
Exclusion criteria
Exclusion criteria: 1.Chronic pelvic pain syndrome (CPPS); 2.??Chronic prostatitis; 3.??History of prostate needle biopsy; 4.??Allergy to local anesthetics; 5.??Coagulation disorders; 6.Acute urinary tract infection with fever??; 7.??Internal/external hemorrhoids, perianal or rectal lesions??; 8.??Patients who withdrew informed consent??; 9.??Investigator-assessed ineligibility for study continuation??;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total Prostate-Specific Antigen; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital Anxiety and Depression Scale (HADS) scoring;Prostate MRI parameters; | — |
Countries
China
Contacts
Public ContactJie Li
Lishui Central Hospital
Outcome results
None listed