Uterine fibroids
Conditions
Interventions
The disodium phosphopropofol combined with sufentanil group:Disodium propofol phosphate combined with sufentanil
The disodium phosphopropofol group:Disodium Phospopropofol
Sponsors
Hangzhou Women's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Age: 18-65 years old; 2.ASA Grade I-III; 3.Select an appropriate time for examination or surgery under general anesthesia; 4.Body mass Index (BMI) : 18-30 kg/m^2; 5.Sign the informed consent form, be able to accept the experimental method, and voluntarily serve as the test subject.
Exclusion criteria
Exclusion criteria: 1.Emergency surgery; 2.Allergic to disodium phosphopropofol or having contraindications for its use; 3.Those who have preoperative consciousness disorders or chronic pain and have been using analgesics, psychotropic drugs (including opioids, NSAIDs, sedatives, antidepressants), or alcohol abusers for a long time; 4.Sedatives, antiemetic drugs, anti-itch drugs, monoamine oxidase inhibitors or antidepressants were used within 24 hours before the operation; 5.History of liver surgery, kidney or liver dysfunction, history of gastrointestinal ulcers or bleeding tendency; 6.Patients with concurrent tumors, severe cardiovascular and cerebrovascular diseases, etc; 7.Researchers who do not agree to participate in or are currently participating in other drug trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Observer’s Assessment of Alertness/Sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral index (BIS) value;Adverse reactions (hypotension; bradycardia; injection pain; hiccups; respiratory depression,etc.);Basic vital signs (blood pressure, heart rate, oxygen saturation); | — |
Countries
China
Contacts
Public ContactZhou Zhenfeng
Hangzhou Women's Hospital
Outcome results
None listed