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Ultrasound-guided paravertebral block versus thoracoscopic intercostal nerve block for analgesia in single manipulation hole thoracoscopic surgery: a single-center, prospective, randomized controlled trial

Ultrasound-guided paravertebral block versus thoracoscopic intercostal nerve block for analgesia in single manipulation hole thoracoscopic surgery: a single-center, prospective, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111351
Enrollment
Unknown
Registered
2025-10-30
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral lung disease

Interventions

A group:Before the start of surgery, ultrasound-guided paravertebral block was performed by the anesthesiologist in the following manner: the study participant had a curved neck and arched back, the p
B group:Liposomes of bupivacaine (strength 20 mL: 226 mg) were injected into a 20 mL syringe and connected to an 8-gauge green infusion needle through a pump tube. During the operation, the lung tissu
C group:Paravertebral block was performed under ultrasound guidance by the anesthesiologist before the start of surgery, and intercostal nerve block was performed under direct thoracoscopic vision by

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years and <= 85 years; 2. Patients scheduled for elective single-port thoracoscopic surgery.

Exclusion criteria

Exclusion criteria: 1. Individuals dependent on analgesics or with a recent history of analgesic use; 2. Individuals with a history of chronic pain or neurological disorders; 3. Those with dysfunction of the heart, liver, kidneys, or other organs; 4. Individuals allergic to the study drug or anesthetics; 5. Those with severe intrathoracic adhesions; 6. Individuals requiring intraoperative conversion to open-chest surgery; 7. Those with active infections or other uncontrolled diseases, or who are pregnant or breastfeeding, making general anesthesia surgery unsuitable; 8. Individuals with psychosomatic disorders or other reasons that prevent them from understanding the study protocol or that may affect the trial; 9. Any other situations deemed by the researchers as unsuitable for participation in this clinical study.

Design outcomes

Primary

MeasureTime frame
visual analogue scale of cough 24h (+/- 6h) after surgery;

Secondary

MeasureTime frame
visual analogue scale of cough when study participants came back to the ward immediately;visual analogue scale of cough 48h (+/- 6h) after surgery;visual analogue scale of cough 72h (+/- 6h) after surgery;visual analogue scale of cough before study participants discharge;visual analogue scale of rest when study participants came back to the ward immediately;visual analogue scale of rest 24h (+/- 6h) after surgery;visual analogue scale of rest 48h (+/- 6h) after surgery;visual analogue scale of rest 72h (+/- 6h) after surgery;visual analogue scale of rest before study participants discharge;numerical rating scale of cough when study participants came back to the ward immediately;numerical rating scale of cough 24h (+/- 6h) after surgery;numerical rating scale of cough 48h (+/- 6h) after surgery;numerical rating scale of cough 72h (+/- 6h) after surgery;numerical rating scale of cough before study participants discharge;numerical rating scale of rest when study participants came back to the ward immediately;numerical rating scale of rest 24h (+/- 6h) after surgery;numerical rating scale of rest 48h (+/- 6h) after surgery;numerical rating scale of rest 72h (+/- 6h) after surgery;numerical rating scale of rest before study participants discharge;postoperative pain pump drug dosage, compression times and withdrawal time (within 72 hours after operation);dosage of analgesics for postoperative rescue (within 72 hours after surgery);

Countries

China

Contacts

Public ContactHanbo Yu

Beijing Hospital

yuhanbo92k10b@163.com+86 136 5102 9519

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026