Open fracture of limbs
Conditions
Interventions
Experimental group: the fractures were fixed with plate screws (Synthes, Solothurn, Switzerland). The bone defect area and plate surface were covered with antibiotic polymethyl methacrylate (PMMA) ce
Control group:For open fractures of the limbs, after emergency debridement, the fractures were stabilized using a combined external fixator, and the remaining wound was covered with VSD.
Sponsors
Wuxi Ninth People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years (inclusive), any gender; (2) Gustilo IIIA/B type limb fractures; (3) Time from injury to medical consultation <24 hours.
Exclusion criteria
Exclusion criteria: (1) Initial emergency surgery was not performed at our hospital; (2) Emergency amputation; (3) History of mental illness and inability to cooperate independently, or history of central nervous system disease; (4) Complicated with severe multiple systemic injuries, unable to undergo secondary surgery in the short term; (5) Complicated with severe cardiovascular, cerebrovascular, respiratory, or hematologic diseases, unable to tolerate surgery or anesthesia; (6) Pregnant or breastfeeding women; (7) Disagree with the surgical plan or subsequent follow-up; (8) Follow-up less than 12 months; (9) Other situations deemed inappropriate for participation in this clinical trial by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| flap survived;bone union;Functional Rating; | — |
Countries
China
Contacts
Public ContactYongjun Rui
Wuxi Ninth People’s Hospital
Outcome results
None listed