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Analysis of intestinal flora and Metabolome Characteristics in Maintenance Hemodialysis patients

Analysis of intestinal flora and Metabolome Characteristics in Maintenance Hemodialysis patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111336
Enrollment
Unknown
Registered
2025-10-29
Start date
2025-10-30
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CKD5?MHD

Interventions

Healthy control group:None
MHD group:None

Sponsors

Wuxi people’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Inclusion criteria for the MHD group:1.Having received maintenance hemodialysis treatment for more than three months; 2.Inclusion criteria for the MHD group:2.Age: 18 to 80 years old, gender not limited; 3.Inclusion criteria for the MHD group:3.Willing to participate after full informed consent. 4.Inclusion criteria for the healthy control group: 1. Age: 18 to 80 years old, gender not limited; 5.Inclusion criteria for the healthy control group: 2.Some family members of the patients requested that they be in good health and have no underlying diseases;

Exclusion criteria

Exclusion criteria: 1.Antibiotics were used within one month before enrollment; 2.Take immunosuppressants, foods or medicines containing probiotics or prebiotics at the same time; 3.The primary diseases are systemic lupus erythematosus, vasculitis, autoimmune diseases, and concurrent malignant tumors, end-stage liver diseases, and chronic intestinal diseases; 4.Gastrointestinal diseases, including irritable bowel syndrome, Crohn's disease or ulcerative colitis; 5.Pregnant or lactating women; 6.long-term bedridden patients who are unable to eat by themselves; 7.Patients with combined mental disorders that affect treatment compliance;

Design outcomes

Primary

MeasureTime frame
Hypersensitive C-reactive protein;Fecal metabolites;Serum metabolites;

Secondary

MeasureTime frame
Serum transferrin;Glycated hemoglobin;Blood routine;Blood biochemistry;Immune inflammatory factors;Serum prealbumin;

Countries

China

Contacts

Public Contactzhijianzhang

Wuxi people’s Hospital

zzjwxyy@163.com+86 510 8535 1161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026