None
Conditions
Interventions
Experimental Group A:Apply Glamour Moisturizing Body Lotion to skin areas other than the face, and use Vitamin E Cream on the face as needed.
Experimental Group B:Apply Glamour Moisturizing Body Lotion to skin areas other than the face, and use Artistry 3D Time-Defying Pink Gold Capsule Serum on the face.
Control Group:Apply Vitamin E Cream to skin all over the body, including the face, as needed.
Sponsors
Dematology Hospital of Southern Medical University
Eligibility
Sex/Gender
Female
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Healthy middle-aged and elderly women aged 45 years or older; 2.With self-reported skin sensitivity, easy flushing, and dryness on the face and body areas; 3.Possessing good communication skills; 4.Willing to comply with all study procedures and ensure follow-up availability during the study period; 5.Able to understand the study process, voluntarily participate in the study, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those who have applied any topical medications to the tested areas within 2 months; 2.Those who have used antihistamines within the past week or immunosuppressants within the past month; 3.Those with clinically unresolved inflammatory skin diseases; 4.Patients with insulin-dependent diabetes mellitus; 5.Patients under treatment for asthma or other chronic respiratory diseases; 6.Those who have received anti-cancer chemotherapy within the past 6 months; 7.Patients with immunodeficiency or autoimmune diseases; 8.Women who are planning to become pregnant, pregnant, or lactating; 9.Those with obvious scars, pigmentation, atrophy, port-wine stains, sunburns, wounds, abrasions, tattoos, or other blemishes on or near the skin test sites that may affect the assessment of study results; 10.Those who have received photorejuvenation, laser therapy, or other aesthetic medical treatments/facial cosmetic procedures (that may affect skin condition) within the past 3 months; 11.Those who have participated in similar facial studies, oral medication trials, or other clinical trials within the past 2 months; 12.Individuals with high physical sensitivity, or those known to be allergic to ingredients in cosmetics/daily chemical products, alcohol, rubber, or medications; 13.Those who need to have long-term exposure to outdoor sunlight due to work or other reasons; 14.Those with other iatrogenic issues that may affect study results (e.g., coagulation disorders, severe hyperglycemia, hypertension, hyperlipidemia, mental illnesses, or history of other serious diseases); 15.Those deemed unsuitable for study participation by other clinical evaluations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor Necrosis Factor-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-1ß (IL-1ß);Interleukin-6 (IL-6);Transepidermal Water Loss (TEWL);Skin Stratum Corneum Moisture Content;Skin Roughness;C-reactive Protein (CRP); | — |
Countries
China
Contacts
Public ContactYe Li
Dematology Hospital of Southern Medical University (Guangdong Provincial Dermatology Hospital)
Outcome results
None listed