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Optimal Epidural Dose for Dixon Method in Penile Concealment Surgery in Preschool Children

Optimal Epidural Dose for Dixon Method in Penile Concealment Surgery in Preschool Children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111325
Enrollment
Unknown
Registered
2025-10-29
Start date
2025-01-17
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

occulting penis

Interventions

Experimental group:Dixon method: The modified Dixon sequential method was used for the experiment. If the caudal epidural block fails, the ropivacaine dose for subsequent subjects is increased
conversely (i.e., negative response), the dose is decreased. The fixed incremental or decremental dose between children is 0.01 mg/kg. The formal test starts from the first crossover wave and continue

Sponsors

The First Affiliated Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
7 Years to 13 Years

Inclusion criteria

Inclusion criteria: School age children aged 7-13 years with ASAI-II grade who have undergone penile concealment surgery

Exclusion criteria

Exclusion criteria: (1) Known cardiopulmonary disease (such as uncorrected congenital heart disease, primary or secondary pulmonary hypertension, tumor or structural lung disease) (2) Neuromuscular diseases (3) Intraspinal block contraindications (abnormal coagulation, spinal deformity) (4) Neurogenesis lag (5) Allergic to ropivacaine (6) Parents refuse their children to participate in the experiment.

Design outcomes

Primary

MeasureTime frame
the 50% effective dose (ED50) and 95% effective dose (ED95);

Secondary

MeasureTime frame
The onset time of sensory block;Efficacy rating of subarachnoid block;the maintenance time of sensory nerve block;the maximum Bromage grade;the maintenance time of motor nerve block;

Countries

China

Contacts

Public ContactBinbin Zhu

The First Affiliated Hospital of Ningbo University

Pingchi1983@126.com+86 159 5748 5723

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026