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A multi-omics prospective cohort study on metabolic risk and treatment response among overweight and obese populations in Shenzhen, China

A multi-omics prospective cohort study on metabolic risk and treatment response among overweight and obese populations in Shenzhen, China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111318
Enrollment
Unknown
Registered
2025-10-29
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight or obesity

Interventions

Weight management group:None

Sponsors

The Seventh Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged between 10 and 65 years. 2.Body mass index (BMI) >= 24, indicating overweight or obesity according to standardized physical examination. 3.Able to communicate effectively and complete questionnaires and follow-up visits. 4.Capable of understanding and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Allergic to the study medication or any of its components. 2.Severe hepatic or renal impairment. 3.Presence of serious metabolic disorders. 4.Presence of systemic infectious diseases. 5.Presence of malignant tumors. 6.Participants expected to have poor compliance. 7.Patients with psychiatric disorders who are unable to cooperate. 8.Participants currently enrolled in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Body composition and visceral fat content;

Secondary

MeasureTime frame
Liver and kidney function;Urinalysis;blood inflammatory markers;Gut microbiota composition and function;insulin;Liver fat content grading and liver elasticity coefficient;lipid profile (four items);fasting blood glucose;

Countries

China

Contacts

Public ContactBin Xia

The Seventh Affiliated Hospital, Sun Yat-sen University

xiabin2011@126.com+86 755 8120 6380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026