Postoperative pulmonary complications (PPCs)
Conditions
Interventions
Observation group:None
Sponsors
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; BMI between 18.5 and 30 kg/m^2; 2.Patients scheduled for elective surgery under general anesthesia with endotracheal intubation (including general surgery, urology, orthopedics, and other non-cardiac, non-thoracic procedures); 3.High risk of PPCs (ARISCAT score >= 45); 4.ASA physical status classification I to III; 5.Signed written informed consent.
Exclusion criteria
Exclusion criteria: 1.Emergency surgery; 2.Pre-existing severe pulmonary disease (e.g., COPD GOLD stage III–IV, active pulmonary infection, pulmonary fibrosis, long-term oxygen therapy, etc.); 3.History of chronic respiratory failure or long-term ventilator dependence; 4.Severe cardiac dysfunction or persistent hypoperfusion (e.g., refractory shock, NYHA class III–IV heart failure); 5.No central venous catheter placed intraoperatively (unable to obtain central venous blood samples); 6.Pregnancy; 7.Cardiac surgery requiring cardiopulmonary bypass; 8.Other conditions deemed unsuitable for inclusion by the investigator (e.g., unexpected intraoperative events preventing measurement of P(v-a)CO2 or completion of follow-up).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative pulmonary complications (PPCs) within 7 days after surgery; | — |
Countries
China
Contacts
Public ContactHaiping Dong
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed