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Efficacy and Safety of Radiofrequency Ablation versus Microwave Ablation for Solid Benign Thyroid Nodules: A Multicenter Retrospective Cohort Study

Efficacy and Safety of Radiofrequency Ablation versus Microwave Ablation for Solid Benign Thyroid Nodules: A Multicenter Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111288
Enrollment
Unknown
Registered
2025-10-29
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Solid Benign Thyroid Nodules

Interventions

Microwave Ablation, MWA:None
Radiofrequency Ablation, RFA:None

Sponsors

Tongji Hospital of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Thyroid nodule with >80% solid component confirmed by ultrasound; 2.Benign pathology (Bethesda II–III) confirmed by ultrasound-guided fine-needle aspiration biopsy; 3.First-time receipt of ultrasound-guided RFA or MWA therapy;

Exclusion criteria

Exclusion criteria: 1.Malignant/suspicious pathology (Bethesda IV–VI); 2.History of ipsilateral thyroid surgery or ablation; 3.Pregnancy or lactation; 4.Other conditions deemed by investigators to contraindicate enrollment or compromise study participation;

Design outcomes

Primary

MeasureTime frame
Incidence of Major Complications;Nodule Volume & Volume Reduction Rate (VRR);—

Secondary

MeasureTime frame
Adverse Event, AE;—

Countries

China

Contacts

Public Contactbai wenkun

Tongji Hospital of Tongji University

doctor505@hotmail.com+86 21 6611 2062

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026