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Evaluation of the Efficacy and Safety of Abdominal Compression Combined with Jaw Thrust in Correcting Hypoxemia During Painless Gastroscopy: A Prospective Randomized Controlled Trial

Evaluation of the Efficacy and Safety of Abdominal Compression Combined with Jaw Thrust in Correcting Hypoxemia During Painless Gastroscopy: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111245
Enrollment
Unknown
Registered
2025-10-28
Start date
2025-10-31
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

Control Group:Jaw Thrust Maneuver: Place both hands behind the mandibular angles on either side of the face, then lift and pull the mandible upward and forward to open the airway. Maintain this positi
Test Group:Combined Intervention of Jaw Thrust + Abdominal Compression

Sponsors

The Second Affiliated Hospital of University of South China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–65 years, regardless of gender; 2. American Society of Anesthesiologists (ASA) Physical Status Classification Grade I–II; 3. Scheduled for elective painless gastroscopy and to receive intravenous anesthesia; 4. Development of hypoxemia (SpO2 =10 seconds) during gastroscopy; 5. Voluntarily signing the informed consent form and having good compliance.

Exclusion criteria

Exclusion criteria: 1. Patients with relative contraindications to digestive endoscopy anesthesia (e.g., ASA Physical Status Classification Grade ? or above; vital organ dysfunction such as recent myocardial infarction or cerebral infarction, severe heart block, malignant arrhythmia, decompensated vital organ function; status asthmaticus; severe pulmonary infection or upper respiratory tract infection; gastrointestinal retention, reflux, or obstruction, etc.); 2. Severe cardiopulmonary dysfunction (e.g., heart failure, chronic obstructive pulmonary disease [COPD], patients requiring oxygen supplementation); 3. Baseline SpO2 = 35 kg/m² (or recorded for subgroup analysis); 9. Emergency gastroscopy or interrupted gastroscopy procedure.

Design outcomes

Primary

MeasureTime frame
Time required for SpO? to recover to >= 95%;

Secondary

MeasureTime frame
Minimum SpO2 Value (%);Average SpO2 Value Within 1 Minute After Intervention;Failure Rate of Hypoxia Correction (Proportion Requiring Endoscope Withdrawal or Mask Ventilation);Examination Interruption Rate;Total Propofol Dosage (mg);Recovery Time (minutes);

Countries

China

Contacts

Public ContactYang Yi

The Second Affiliated Hospital of University of South China

yangyi@usc.edu.cn+86 198 8469 2636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026