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Cerebral blood flow changes in patients with PFP under different functional tasks: a fNIRS study

Cerebral blood flow changes in patients with PFP under different functional tasks: a fNIRS study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111237
Enrollment
Unknown
Registered
2025-10-28
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral Pain

Interventions

Patellofemoral pain (PFP) group :None

Sponsors

Beijing Sport University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: PFP group: 1. Age between 18 and 45 years old; 2. There is pain in the patellofemoral joint in one lower limb, which is determined by meeting all of the following criteria: (1) Pain around the patella or in the anterior part of the knee lasting for >= 6 weeks, and the VAS score for patellofemoral joint pain >= 3 points; (2) Pain occurs in at least 2 of the following functional activities: prolonged sitting with knee flexion, going up and down stairs, squatting, kneeling, running, jumping; (3) Positive patellar grinding test or positive tenderness in the joint surface margin of the patella. 3. During the study period, they are willing to give up any treatment for patellofemoral joint pain other than the study intervention. Healthy group: 1. Age and gender are matched with the PFP pain group; 2. No functional or organic diseases in the past, no lower limb injury; 3. No continuous or intermittent pain in the past three months; 4. The subjects signed the informed consent form.

Exclusion criteria

Exclusion criteria: PFP group: 1. Has a history of knee surgery, or has patellar tendinitis, patellar dislocation, ligament injuries of the knee joint, meniscus injuries or other structural injuries or related neurological disorders; 2. Has acute joint injuries, such as acute sprains and ligament tears, with acute stage, persistent edema, severe open wounds, fractures, etc.; 3. Has severe liver, kidney, cardiovascular diseases, tumors, severe intervertebral disc or vertebral body lesions, and osteoporosis, etc. which seriously affect joint movement and function; 4. May have diseases that affect muscle strength, such as diabetes, rheumatoid arthritis, etc.; 5. Has recently used or taken corticosteroid anti-inflammatory drugs externally or internally; 6. The subjects cannot tolerate near-infrared brain functional imaging examination. Healthy group: 1. Female participants who are pregnant; 2. Participants who are involved in other studies that may affect the patellofemoral region; 3. Participants who cannot tolerate near-infrared brain functional imaging examination.

Design outcomes

Primary

MeasureTime frame
Functional near-infrared brain imaging test;

Secondary

MeasureTime frame
Single Leg Squat;Unilateral stance;Tampa Scale of Kinesiophobia (TSK-17);

Countries

China

Contacts

Public ContactSinuo Pang

Beijing Sport University

pangsinuo0909@163.com+86 199 3287 7237

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026