Motor and Cognitive Impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 60 and 85 years; 2. Presence of one or more motor or cognitive impairments, including restricted joint mobility, decreased muscle strength, abnormal muscle tone, reduced muscle endurance, upper limb incoordination, fine motor deficits, balance dysfunction, gait abnormalities, tremor, cardiopulmonary dysfunction, memory impairment, visuospatial deficits, executive dysfunction, calculation difficulty, attention deficit, disorientation, speech impairment, or sensory-perceptual disturbances; 3. Willingness to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe cognitive impairment who are wholly incapable of comprehending the trial content and providing informed consent; 2. Individuals with unstable medical conditions such as active bleeding, severe infection, serious cardiopulmonary disease, multiple organ failure, brain tumours, or severe psychiatric disorders; 3. Individuals with new-onset fractures or open wounds; 4. Individuals with severe visual or hearing impairments, such as colour blindness or deafness; 5. Individuals currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor function behavioral assessment (including the 6-minute walk test, handgrip strength test, and manual muscle testing).;Cognitive function behavioral assessment (including the Mini-Mental State Examination and the Montreal Cognitive Assessment).;Activities of daily living assessment (including the IADL scale, BADL scale, and FIM scale).;Multimodal neurophysiological assessment (including resting-state electroencephalography, event-related potentials, and surface electromyography).; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Sun Yat-Sen University