osteoporosis
Conditions
Interventions
Oral lithium carbonate group:None
Group without using lithium carbonate (control group):None
Sponsors
Wuhan Mental Health Center
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Psychiatric patients taking lithium carbonate for the first time; 2. Primary osteoporosis diagnosed by bone density measurement T <= -2.5 and laboratory examination in accordance with the Diagnosis and Treatment Guidelines for Primary Osteoporosis (2022); 3. Women who experience menopause or men over 60 years old; 4. The subjects voluntarily participated and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous history of using estrogen and anti osteoporosis drugs; 2. Using drugs that cause bone damage, such as glucocorticoids (>= 7.5mg/d prednisolone for more than 3 months); 3. Participated in other clinical trials within the past three months; 4. Women who are breastfeeding, pregnant, or preparing for pregnancy; 5. Patients who are known to be allergic to the components of the test sample or its analogues, as well as patients with oral contraindications; 6. Patients with poor treatment compliance as determined by researchers; 7. Diseases that may interfere with research results and affect bone metabolism, as well as other severe, acute, or chronic diseases; 8. Researchers believe that other situations are not suitable for inclusion or are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density;Bone turnover markers; | — |
Countries
China
Contacts
Public ContactMa Jingwei
School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed