Construction of a quantitative model of hepatic steatosis and fibrosis in MAFLD based on multi-parameter ultrasound

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500111211

Enrollment

Unknown

Registered

2025-10-28

Start date

2025-12-24

Completion date

Unknown

Last updated

2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic-related fatty liver disease

Interventions

Gold Standard:Magnetic Resonance Imaging

Index test:Ultrasound-derived fat fraction Shear wave elastography

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years. 2. Able to tolerate a complete liver ultrasound examination. 3. MRI examination acceptable.

Exclusion criteria

Exclusion criteria: 1. Age 1 week. 4. Presence of other liver diseases: alcoholic liver disease (defined by current AUD criteria: daily alcohol intake > 42 g for men or > 28 g for women; or binge drinking > 70 g for men or > 56 g for women within 2 h), viral infection (HIV, HBV, HCV), drug-induced liver injury, or autoimmune hepatitis.

Design outcomes

Primary

Measure	Time frame
Ultrasound-derived fat fraction;MRI-PDFF;Specificity;Intraclass Correlation Coefficient;Area Under Curve;Shear wave elastography, SWE;Sensitivity;	—

Countries

China

Contacts

Public ContactQi Ruixinang

Hangzhou First People's Hospital

qirx1816@126.com+86 571 5600 5600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026