Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Conform to the diagnostic criteria for stroke specified in Diagnostic Points for Various Major Cerebrovascular Diseases in China formulated by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association, and confirmed by cranial CT or MRI; 2. First onset of stroke; 3. Disease course ranging from 2 weeks to 1 month; 4. Age between 18 and 80 years old; 5. Clear consciousness, able to understand and execute instructions: score of >=20 on the Montreal Cognitive Assessment Scale (MoCA); 6. Unilateral onset, with muscle strength of flexors and extensors of the affected knee joint >= Grade 3, Brunnstrom stage of the affected lower limb >= Stage III, and presence of proprioceptive impairment (hypoesthesia or absence of proprioception) confirmed by proprioception assessment; 7. Patients or their family members have signed the informed consent form and voluntarily participate in the study.
Exclusion criteria
Exclusion criteria: 1. Severe lower limb spasticity, with a modified Ashworth scale score of >=3 for knee flexors or extensors; 2. Patients with lower limb deep sensory impairment caused by other factors, such as spinal cord injury; 3. Etiologies leading to lower limb knee joint pain, such as sprains, acute arthritis, meniscus injury, etc.; 4. Complicated with unilateral neglect and apraxia; 5. Presence of hepatic, renal, cardiac or other organ insufficiency, or malignant hypertension; 6. A history of anxiety or depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nottingham Sensory Assessment;Joint Position Reproduction Test;Threshold To Detection of Passive Motion;Somatosensory Evoked Potentials ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer assessment lower extremity;Berg Balance Scale;Modified Barthel Index; | — |
Countries
China
Contacts
Beijing Tiantan Hospital, Capital Medical University