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Isokinetic Training for Proprioceptive Impairment in Stroke: A Randomized Controlled Trial on Lower-Extremity Functional Recovery

Isokinetic Muscle Strength Training for Lower-Limb Functional Recovery in Convalescent Stroke Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111205
Enrollment
Unknown
Registered
2025-10-28
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Control group:Conventional rehabilitation
Trial group:Conventional rehabilitation combined with isokinetic muscle strength training

Sponsors

Department of Rehabilitation Medicine, Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Conform to the diagnostic criteria for stroke specified in Diagnostic Points for Various Major Cerebrovascular Diseases in China formulated by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association, and confirmed by cranial CT or MRI; 2. First onset of stroke; 3. Disease course ranging from 2 weeks to 1 month; 4. Age between 18 and 80 years old; 5. Clear consciousness, able to understand and execute instructions: score of >=20 on the Montreal Cognitive Assessment Scale (MoCA); 6. Unilateral onset, with muscle strength of flexors and extensors of the affected knee joint >= Grade 3, Brunnstrom stage of the affected lower limb >= Stage III, and presence of proprioceptive impairment (hypoesthesia or absence of proprioception) confirmed by proprioception assessment; 7. Patients or their family members have signed the informed consent form and voluntarily participate in the study.

Exclusion criteria

Exclusion criteria: 1. Severe lower limb spasticity, with a modified Ashworth scale score of >=3 for knee flexors or extensors; 2. Patients with lower limb deep sensory impairment caused by other factors, such as spinal cord injury; 3. Etiologies leading to lower limb knee joint pain, such as sprains, acute arthritis, meniscus injury, etc.; 4. Complicated with unilateral neglect and apraxia; 5. Presence of hepatic, renal, cardiac or other organ insufficiency, or malignant hypertension; 6. A history of anxiety or depression.

Design outcomes

Primary

MeasureTime frame
Nottingham Sensory Assessment;Joint Position Reproduction Test;Threshold To Detection of Passive Motion;Somatosensory Evoked Potentials ;

Secondary

MeasureTime frame
Fugl-Meyer assessment lower extremity;Berg Balance Scale;Modified Barthel Index;

Countries

China

Contacts

Public ContactZhang Yumei

Beijing Tiantan Hospital, Capital Medical University

zhangyumei95@aliyun.com+86 136 9140 4106

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026