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Innovation and application of nutrition intervention in the elder based on intestinal TLR4 regulation of glucose and lipid metabolism

Innovation and application of nutrition intervention in the elder based on intestinal TLR4 regulation of glucose and lipid metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111198
Enrollment
Unknown
Registered
2025-10-28
Start date
2023-02-24
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Control:None
First three months:Taking the capsules of blueberry anthocyanin extract in the first three months
Last three months:Taking the capsules of blueberry anthocyanin extract in the last three months
Six months:Taking the capsules of blueberry anthocyanin extract for six months

Sponsors

The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >= 60 years old; Type 2 diabetes; Poor blood sugar control; Fasting blood glucose >= 7 mmol/L, glycated hemoglobin >= 6.5%; Able to eat orally; Stable health status and smooth communication with researchers; Voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: The patient has cognitive impairment and cannot cooperate with the study; The patient has other serious illnesses, such as dysfunction of important organs such as the heart, lungs, and kidneys; Existence of autoimmune diseases; The patient has a history of surgical treatment in the past six months; Poor compliance and difficulty in follow-up.

Design outcomes

Secondary

MeasureTime frame
Biochemical Parameters (TGT, CHO, LDL, HDL);Body weight;Urinalysis;Symptoms of visual fatigue;Blood routine;Height;Systolic blood pressure;Diastolic blood pressure;ALT;AST;LDH;UR ;CR;Intraocular pressure;Sight;

Primary

MeasureTime frame
Blood glucose;Glycosylated hemoglobin;Optical Coherence Tomography Indicators;Insulin;C-peptide;

Countries

China

Contacts

Public ContactShan Lu

Jiangsu Province Hospital

myfriend007@126.com+86 151 0516 7713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026