Difficult airway
Conditions
Interventions
Remimazolam group (group R):Intravenous drip of remimazolam 0.15mg/kg
Dexmedetomidine group (group D):Patients in the dexmedetomidine group received an intravenous pump infusion of dexmedetomidine at a dose of 1.0 µg/kg
Midazolam group (group M):Patients in the midazolam group received an intravenous bolus of midazolam at a dose of 0.04 mg/kg
Sponsors
The First People’s Hospital of Jingzhou
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-60 years old 2.BMI: 18.5-23.9kg/m ^2 3.ASA classification I-II. 4. Preoperative assessment of difficult airway (guideline criteria: Mallampati grade III or IV, mouth opening <3cm, nail and chin distance <6cm or less than the width of three transverse fingers of the examinee, the anterior extension of the lower jaw cannot align the upper and lower incisors, abnormal extension of the atlas joint, meeting any one of the above is acceptable)
Exclusion criteria
Exclusion criteria: 1.Allergic to benzodiazepines or flumacinib 2. People with airway hyperresponsiveness diseases (combined with chronic bronchitis, asthma and other respiratory diseases) 3. Fill your stomach 4. Reflux esophagitis, intestinal obstruction, etc 5. Have clinically relevant cardiovascular conditions (such as sinus bradycardia or severe arrhythmia) 6. People with neuropathy, mental illness or allergic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intubation Numbers;Eyelash reflex vanishing time;Time required for intubation;Record the patients' mean arterial pressure (MAP), heart rate (HR), and oxygen saturation (SpO2) at each time point: before induction (T0), before intubation (T1), immediately after intubation (T2), a;Postoperative complications; | — |
Countries
China
Contacts
Public ContactTang Li
The First People’s Hospital of Jingzhou
Outcome results
None listed