Comparative Study on Efficacy of HTO versus HTO Combined with Cartilage Repair in the Treatment of Medial Compartment Knee Osteoarthritis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500111186

Enrollment

Unknown

Registered

2025-10-27

Start date

2025-11-01

Completion date

Unknown

Last updated

2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Test Group:High tibial Osteotomy Combined with Cartilage Repair

Control Group:High tibial Osteotomy

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with medial compartment knee osteoarthritis who are males aged 5° or (HKA >5° and MPTA <87°).

Exclusion criteria

Exclusion criteria: 1. Patients with severe medial compartment joint damage (Ahlbäck grade II or higher). 2. Patients with concomitant patellofemoral osteoarthritis or inflammatory joint disease. 3. Patients with a range of motion 5°. 4. Patients with a BMI >30 kg/m². 5. Patients unable to tolerate magnetic resonance imaging (MRI) scans. 6. Patients unable to complete subjective questionnaires or mentally unfit to provide informed consent. 7. Patients whose general medical condition precludes tolerance for surgery.

Design outcomes

Primary

Measure	Time frame
Magnetic Resonance Observation of Cartilage Repair Tissue Score;	—

Secondary

Measure	Time frame
VAS score;Function and activity level;arthroscopic International Cartilage Repair Society (ICRS) grade;	—

Countries

China

Contacts

Public ContactXiao Chen

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

sirchenxiao@126.com+86 135 6466 1943

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026