Epithelial ovarian cancer
Conditions
Interventions
Gold Standard:Pathological diagnosis was adopted as the gold standard in this study
Index test:Detection of human exosomes CA125, HE4 and C5a(OCS)
Sponsors
West China Second University Hospital of Sichuan University (WCSUH- SCU)
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Imaging studies (US, CT, MR) suggest space-occupying lesions in the ovaries and fallopian tubes (adnexal area). 2.Serum CA125 ranges from 35 to 200U/ml; 3.Anti-tumor treatment was not carried out before obtaining the OCS blood samples; 4.The research subjects have signed the informed consent and can obtain the complete information and medical records of the patients; 5.Over 18 years old;
Exclusion criteria
Exclusion criteria: 1.There are primary tumors in other organs; 2.Combined with other serious internal medicine diseases: severe abnormalities of heart, liver and kidney functions; Immune or hematological system diseases Severe body Body injury Uncontrolled infectious diseases; 3.Those with poor basic conditions who cannot tolerate surgery (using physical strength scores); 4.Special groups of people who are unable to cooperate with researchers; 5.Previously diagnosed with malignant tumors and received anti-tumor drugs or radiotherapy; 6.There is no pathological diagnosis after the operation or the pathological type cannot be clearly defined; 7.Primary tumors that are not of ovarian or fallopian tube origin are found through imaging or surgery; 8.A history of blood transfusion within three months; 9.After comprehensive assessment by the researcher, it is found that one is not suitable to participate in the research; 10.Has participated in other research projects;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity ;specificity; | — |
Countries
China
Contacts
Public ContactYuedong He
West China Second University Hospital of Sichuan University (WCSUH- SCU)
Outcome results
None listed