Uterine fibroids
Conditions
Interventions
Butorphanol group (B group):0.9% Normal Saline
Low-dose lidocaine group (D group):1 mg/kg/h lidocaine analgesic pump infusion
High-dose lidocaine (G group):1.5mg/kg/h lidocaine analgesia pump infusion
Sponsors
Chengdu Wenjiang District People’s Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Age: 18-80 years old; 2. 18 < BMI < 30 kg/m^2; 3. American Society of Anesthesiologists (ASA) class I to III; 4. Exclude patients with severe bradycardia, arrhythmias, or other cardiac dysfunctions; 5. Patients scheduled for elective laparoscopic total hysterectomy.
Exclusion criteria
Exclusion criteria: 1. Patients with II/III degree atrioventricular block or those who develop severe bradycardia during the perioperative period requiring urgent management, 2. Critically ill patients, including those with poorly controlled blood pressure: systolic BP >= 180 mmHg and/or diastolic BP >= 105 mmHg, severe hepatic and renal dysfunction, etc.; 3. Pregnant or breastfeeding women; 4. Patients allergic to amide-type local anesthetics; 5. Surgery duration > 6 hours; 6. Patients who refuse to sign the consent form; 7. Patients with severe preoperative anemia or requiring blood transfusion during surgery; 8. Patients with liver dysfunction (Child-Pugh score C); 9. Any other reasons deemed by the investigator as making the patient unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative resting and exercise visual scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of effective presses, number of rescue analgesia administrations, and total dose;Restore Quality QoR-15 Score;Time of first urination/defecation;Incidence of nausea and vomiting;Time of first ambulation;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactHe Danyang
Chengdu Wenjiang District People’s Hospital
Outcome results
None listed