Acute Respiratory Distress Syndrome
Conditions
Interventions
Trial group:None
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years and <= 80 years, gender not restricted; 2. Within one week of onset, there are known clinical manifestations of respiratory system impairment or new/accelerated respiratory symptoms; 3. Chest imaging suggests weakened lung transparency, which cannot be fully explained by pleural effusion, lobar pneumonia, atelectasis, pulmonary nodules, etc. 4. Respiratory failure cannot be fully explained by heart failure or fluid overload, and excludes pulmonary edema caused by increased hydrostatic pressure; 5. Blood gas analysis: P/F <= 300 mmHg; 6. Undergoing invasive mechanical ventilation treatment; 7. Need for fiberoptic bronchoscopy examination or treatment; 8. The patient or legal representative signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with underlying diseases whose expected survival time is less than 28 days, such as terminal malignant tumors, cardiac arrest within 30 days before enrollment, terminal lung diseases, etc. 3. Patients with severe diseases such as severe heart failure (NYHA class IV), chronic obstructive pulmonary disease, long-term kidney dialysis, liver failure, immunosuppression, etc. 4. Patients whose attending doctors consider not suitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extracellular fluid viscosity; | — |
Countries
China
Contacts
Public ContactRuwei Huo
The First People’s Hospital of Lianyungang
Outcome results
None listed