benign prostatic hyperplasia
Conditions
Interventions
Propofol Group :Anesthesia induction: Propofol
Anesthesia maintenance: Continuous infusion of propofol and remifentanil (analgesic)
Remimazolam Group:Anesthesia induction: Remimazolam
Anesthesia maintenance: Continuous infusion of Remimazolam and Remifentanil (analgesic)
Sponsors
Meishan People's Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. All meet the surgical indications for transurethral plasma resection of the prostate; 2. All are scheduled to undergo elective transurethral plasma resection of the prostate; 3. Age >= 65 years; 4. Quick frailty questionnaire (FRAIL) score >= 3 points; 5. All are planned to undergo general anesthesia; 6. Anesthesia classification II~III; 7. Patients and their families are informed about this study and have signed the consent form.
Exclusion criteria
Exclusion criteria: 1. Accompanied by cardiovascular diseases (coronary heart disease, arrhythmia, hypertension, etc.); 2. Accompanied by metabolic diseases (diabetes); 3. Accompanied by liver or kidney dysfunction, or coagulation disorders; 4. Accompanied by psychiatric disorders, unable to cooperate with the investigator; 5. History of dependence on sedatives or analgesics, and history of alcoholism; 6. Body mass index >30 kg/m^2; 7. History of prostate surgery; 8. Expected surgery duration >2 hours; 9. Allergy or intolerance to anesthetics used in this study; 10. Patients with myasthenia gravis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Monitor vital sign fluctuations; | — |
Secondary
| Measure | Time frame |
|---|---|
| Onset and recovery of anesthesia;Cognitive function ;Adverse reaction; | — |
Countries
China
Contacts
Public ContactLi Na
Meishan People's Hospital
Outcome results
None listed