post-stroke cognitive impairment
Conditions
Interventions
control group:common rehabilitation+pseudo-stimulation
observation group:common rehabilitation+high-frequency repetitive transcranial magnetic stimulation
Sponsors
Affiliated Hospital of Nantong University
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. meets the diagnostic criteria for stroke and is confirmed by cranial CT or MRI imaging; 2. presence of cognitive impairment (Montreal Cognitive Assessment, MoCA<26); 3. first stroke with stroke duration between 1 and 6 months; 4. 30 years <= age <= 75 years; 5. no severe aphasia and able to complete cognitive tests; 6. overall stabilisation of the condition, with clear mental status and stable vital signs; 7. Normal pre-stroke cognitive function; 8. The person himself/herself or legal guardian agrees and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Non first stroke; 2.CT/MRI confirmed complete damage to the left prefrontal cortex; 3.Transcranial surgery or skull defect; 4.Metal or pacemaker implants; 5.History of brain tumors, history of brain trauma, history of seizures, and risk of seizures; 6.Cognitive decline before stroke; 7.The Hamilton Depression Scale (HAMD) score is greater than 17 points; 8.Any neurological and psychiatric comorbidities and emotional disorders that may affect the results; 9.Medications such as antibiotics and probiotics that have been proven to have an impact on the gut microbiota and its metabolite structure; 10.Any other factors that may affect cognitive assessment and treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| daily living ability;gut microbiota; | — |
Countries
China
Contacts
Public ContactJie Gao
Affiliated Hospital of Nantong University
Outcome results
None listed