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Research on Artificial Intelligence-Based Facial Activity and Speech-Related Patterns and Their Digital Biomarkers in Parkinson's Disease

Research on Artificial Intelligence-Based Facial Activity and Speech-Related Patterns and Their Digital Biomarkers in Parkinson's Disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111135
Enrollment
Unknown
Registered
2025-10-27
Start date
2023-07-25
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

Gold Standard:2015 MDS Parkinson's disease diagnostic criteria.?2017 Chinese expert consensus diagnostic criteria for multiple system atrophy?2016 Chinese clinical diagnostic criteria for progressive

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for Parkinson's Disease (PD) Group: (1) Diagnostic Criteria: Meet the diagnostic criteria for Parkinson's disease established by the Movement Disorder Society (MDS) in 2015; (2) Age Range: 18–75 years old; (3) Disease Severity: Early-stage PD: Hoehn-Yahr score <= 2.5 points. Mid-to-late-stage PD: Hoehn-Yahr score 2.5–5 points; (4) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording; (5) Informed Consent: Signed informed consent form. 2. Inclusion Criteria for Parkinson's Plus Syndromes (MSA-P, PSP) Group: (1) Age Range: 18–75 years old;(2) Diagnostic Criteria: MSA patients must meet the diagnostic criteria established by the [Chinese Expert Consensus on the Diagnosis of Multiple System Atrophy, 2017]. PSP patients must meet the diagnostic criteria established by the [Chinese Clinical Diagnostic Criteria for Progressive Supranuclear Palsy, 2016 Edition]; (3) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording; (4) Informed Consent: Signed informed consent form.;

Exclusion criteria

Exclusion criteria: 1History of cerebrovascular disease, head trauma, hydrocephalus, brain tumors, or intracranial surgery;2Presence of metal implants, cardiac pacemakers, or other metallic foreign bodies (applies to PD patients); 3.Severe dyskinesia in PD patients that would compromise cooperation with video/audio recording; 4.Mini-Mental State Examination (MMSE) score <= 24 points.

Design outcomes

Primary

MeasureTime frame
Efficacy;Precision;Recall;

Countries

China

Contacts

Public ContactLingyan Ma

Beijing Tiantan Hospital, Capital Medical University

Jennifer_MLY@163.com+86 10 5997 6611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026