Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Parkinson's Disease (PD) Group: (1) Diagnostic Criteria: Meet the diagnostic criteria for Parkinson's disease established by the Movement Disorder Society (MDS) in 2015; (2) Age Range: 18–75 years old; (3) Disease Severity: Early-stage PD: Hoehn-Yahr score <= 2.5 points. Mid-to-late-stage PD: Hoehn-Yahr score 2.5–5 points; (4) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording; (5) Informed Consent: Signed informed consent form. 2. Inclusion Criteria for Parkinson's Plus Syndromes (MSA-P, PSP) Group: (1) Age Range: 18–75 years old;(2) Diagnostic Criteria: MSA patients must meet the diagnostic criteria established by the [Chinese Expert Consensus on the Diagnosis of Multiple System Atrophy, 2017]. PSP patients must meet the diagnostic criteria established by the [Chinese Clinical Diagnostic Criteria for Progressive Supranuclear Palsy, 2016 Edition]; (3) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording; (4) Informed Consent: Signed informed consent form.;
Exclusion criteria
Exclusion criteria: 1History of cerebrovascular disease, head trauma, hydrocephalus, brain tumors, or intracranial surgery;2Presence of metal implants, cardiac pacemakers, or other metallic foreign bodies (applies to PD patients); 3.Severe dyskinesia in PD patients that would compromise cooperation with video/audio recording; 4.Mini-Mental State Examination (MMSE) score <= 24 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy;Precision;Recall; | — |
Countries
China
Contacts
Beijing Tiantan Hospital, Capital Medical University