Knee joint diseases
Conditions
Interventions
Sponsors
Fuyang People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing primary unilateral total knee arthroplasty (TKA); 2. Age ranging from 40 to 80 years; 3. American Society of Anesthesiologists (ASA) physical status classification of grades ? to ?.
Exclusion criteria
Exclusion criteria: 1. Patients with failure of vital organs such as heart and lung; 2.Abnormal liver or kidney function (ALT/AST > 1.5 times the normal value, blood urea nitrogen (BUN) > 8.3 mmol/L, serum creatinine (Scr) > 115 µmol/L); 3. Diabetic patients with poor glycemic control and judged by the researcher to have infection risk; 4. Combined with disturbance of consciousness or mental disorders; 5. History of open knee surgery; 6. Neuromuscular dysfunction affecting lower limb function; 7. Allergy to drugs used in this study; 8. Opioid addiction; 9. Language barriers or inability to complete the Visual Analogue Scale (VAS) for pain assessment; 10. Patients deemed unsuitable for participation by the researcher due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total postoperative sufentanil dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative VAS pain scores at rest and during movement;Postoperative recovery quality;Postoperative incidence of chronic pain;Adverse reaction;Time of first use of analgesics after surgery;PCIA effective compression frequency; | — |
Countries
China
Contacts
Public ContactWenmeng Han
Fuyang People's Hospital
Outcome results
None listed