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Study on the Dynamic Assessment of Chronic Ischemia and the Brain Network Mechanisms of Cognitive Dysfunction in Moyamoya Disease Based on an optically pumped magnetometers Magnetoencephalography System

Study on the Dynamic Assessment of Chronic Ischemia and the Brain Network Mechanisms of Cognitive Dysfunction in Moyamoya Disease Based on an optically pumped magnetometers Magnetoencephalography System

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111098
Enrollment
Unknown
Registered
2025-10-26
Start date
2025-10-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moyamoya Disease

Interventions

Healthy control group:None

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for Moyamoya disease as confirmed by DSA/MRA; 2. Signed informed consent; 3. Age over 16 years and under 60 years; 4. Baseline mRS score <=2; 5. No significant brain structural lesions

Exclusion criteria

Exclusion criteria: 1. Patients with a combination of atherosclerosis, autoimmune diseases, meningitis, Down syndrome, cranial trauma, or head radiation that may lead to secondary cerebrovascular lesions causing Moyamoya syndrome; 2. Age under 18 or over 60; 3. Refusal to participate in this study; 4. Presence of intracranial aneurysms, cerebrovascular malformations, brain tumors, or hydrocephalus; 5. Missing imaging data or imaging quality insufficient for analysis; 6. Refusal or inability to undergo imaging follow-up.

Design outcomes

Primary

MeasureTime frame
Cognitive function assessment;

Secondary

MeasureTime frame
MEG data;MRI data;

Countries

China

Contacts

Public ContactQian Zhang

Beijing Tiantan Hospital Affiliated to Capital Medical University

zhangqianttchina@163.com+86 10 5997 8317

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026