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Postoperative online adaptive radiotherapy for endometrial cancer with an integrated CT-LINAC

Postoperative online adaptive radiotherapy for endometrial cancer with an integrated CT-LINAC

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111085
Enrollment
Unknown
Registered
2025-10-24
Start date
2025-10-27
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

oART:Using an integrated CT linear accelerator (uRT-linac 506c) for postoperative online adaptive radiotherapy of endometrial cancer.

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Voluntarily agree to participate in this study and sign a written informed consent form prior to treatment. 2.Postoperative pathological diagnosis of endometrial carcinoma with indications for adjuvant radiotherapy. 3.Postoperative imaging assessment confirming absence of distant metastasis. 4.Karnofsky score >= 60. 5.Age 18–85 years. 6.Able to comply with study requirements, demonstrate good adherence, and agree to follow-up.

Exclusion criteria

Exclusion criteria: 1.Prior pelvic radiotherapy. 2.Requirement for simultaneous lymph node or parametrial boost. 3.Concurrent serious organic diseases that would impair tolerance or markedly increase radiotherapy risk, including but not limited to central nervous system disorders, severe cardiac disease (e.g., unstable angina, recent myocardial infarction, NYHA class III–IV heart failure), severe hepatic insufficiency, severe renal failure, significant coagulopathy, or active infections requiring strict control. 4.Interruption of current treatment for any reason or anticipated inability to complete the planned radiotherapy course. 5.Participation in another clinical trial or currently within another trial’s observation/follow-up period. 6.Inability to comply with post-treatment follow-up. 7.Any other condition deemed by the investigator to make the subject unsuitable for participation.

Design outcomes

Primary

MeasureTime frame
Treatment Duration;

Secondary

MeasureTime frame
Dosimetric Parameters;

Countries

China

Contacts

Public ContactAng Qu

Peking University Third Hospital

qa11980@sina.com+86 10 8226 4910

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026