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Survival Benefits and Risk Assessment of Extended Criteria Donor Grafts in MELD Score-Stratified Liver Transplant Recipients: A Retrospective Cohort Study

Survival Benefits and Risk Assessment of Extended Criteria Donor Grafts in MELD Score-Stratified Liver Transplant Recipients: A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111064
Enrollment
Unknown
Registered
2025-10-24
Start date
2025-10-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-Stage Liver Disease

Interventions

Low-MELD - Standard Liver Group:None
High-MELD - Standard Liver Group:None
Low-MELD - Marginal Liver Group:None
High-MELD - Marginal Liver Group:None

Sponsors

The First Affiliated Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who underwent adult (>=18 years of age) orthotopic whole liver transplantation at the Liver Transplant Center of the First Affiliated Hospital, Zhejiang University School of Medicine between January 1, 2017, and May 30, 2023.

Exclusion criteria

Exclusion criteria: 1. Patients who received split liver transplantation or multiple organ transplantation. 2. Pediatric recipients (<18 years of age). 3. Patients with missing key clinical data or lost to follow-up.

Design outcomes

Primary

MeasureTime frame
Perioperative survival rate (patient survival at 1 month and 3 months post-surgery);Short-term survival rate (patient survival at 1 year post-surgery);Overall survival rate (long-term survival from transplantation to last follow-up or death);

Secondary

MeasureTime frame
Graft-related complication rate (including biliary complications, vascular complications, and hemorrhagic complications);

Countries

China

Contacts

Public ContactDuan Xin

The First Affiliated Hospital, Zhejiang University School of Medicine

duanxin8820@163.com+86 139 5812 6522

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026