Acute myeloid leukemia,high-risk myelodysplastic syndrome (MDS)
Conditions
Interventions
Observational group:None
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosed with acute myeloid leukemia (AML); 2. Myelodysplastic syndromes (MDS) with high-risk stratification according to the International Prognostic Scoring System (IPSS) or WHO classification; 3. Age >= 14 years; 4. Treatment regimen includes venetoclax (VEN), such as VEN + hypomethylating agents (HMAs) or VEN + low-dose cytarabine (LDAC).
Exclusion criteria
Exclusion criteria: 1. Acute promyelocytic leukemia (APL); 2. History of drug or alcohol abuse; 3. Missing relevant data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Performance Status;Peripheral Blood Picture;Underlying Disease;Genetic Information;Previous Treatment Selection of Inhibitors (e.g., FLT3 Inhibitors, IDH Inhibitors, etc.);HMA Drug Effect;Model Prediction Accuracy; | — |
Countries
China
Contacts
Public ContactXu Shuangnian
The First Affiliated Hospital of Army Medical University
Outcome results
None listed