atrial fibrillation
Conditions
Interventions
POAF (The treatment plan is the same as the standard surgical procedure for off-pump coronary artery bypass grafting. After opening the pericardium during the operation, the pericardial fluid that wou
Non POAF (The treatment plan is the same as the standard surgical procedure for off-pump coronary artery bypass grafting. After opening the pericardium during the operation, the pericardial fluid that
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. I will undergo elective isolated non-stop coronary artery bypass surgery in our hospital, which is in line with the surgical indications for coronary artery bypass grafting (left main coronary artery lesion with stenosis greater than 50%; pseudo-left main coronary artery lesion, i.e., simultaneous presence of more than 75% stenosis in the proximal parts of the anterior descending branch and circumflex branch; triple-vessel lesion, stenosis greater than 75%; coronary heart disease combined with left heart dysfunction; failed interventional treatment or restenosis). 2. The patient's age is between 40 and 80 years old. 3. The patient and their family members have good compliance, fully understand the project content, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who underwent the surgery despite not meeting the indications for coronary artery bypass grafting due to other reasons; 2. Patients who underwent bypass surgery without bypassing the heart without stopping the heart; 3. Patients with a history of chronic lung diseases such as COPD, asthma, or autoimmune diseases such as systemic lupus erythematosus, Sjogren's syndrome, or those with concurrent malignant tumors; 4. Patients with a history of renal insufficiency, including acute kidney injury (SCr increased by 50% within 7 days or 0.3 mg/dL within 48 hours) or chronic kidney disease (GFR < 60 ml/min per 1.73m^2 for 3 months); 5. Patients with a history of liver insufficiency; 6. Patients with a history of atrial fibrillation, requiring control of ventricular rate through medication; 7. Patients and their families have poor compliance, or are unable to fully understand the project content, or refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative new-onset atrial fibrillation; | — |
Countries
China
Contacts
Public ContactLuPeng
The First Affiliated Hospital with Nanjing Medical University
Outcome results
None listed