Sepsis/septic shock
Conditions
Interventions
Observation group undergoing hemofiltration or hemofiltration dialysis treatment:None
Sponsors
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with sepsis who have undergone hemofiltration or hemofiltration dialysis treatment 2. Age > =18 years old
Exclusion criteria
Exclusion criteria: 1.Patients who undergo hemofiltration treatment for reasons not related to sepsis, such as chronic heart or kidney failure or electrolyte imbalance, etc 2. Patients who received hemofiltration or hemoperfusion treatment within 7 days before enrollment 3. Patients with severe organ failure and an APACHE II score of >=40 at the time of enrollment 4. Patients who have undergone plasma exchange, double plasma exchange or other blood purification treatments 5. Infection or carrier of human immunodeficiency virus 6. Patients during pregnancy and the puerperium 7. Patients with incomplete clinical data and missing values exceeding 20%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality at 30 day; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of days on mechanical ventilation, number of days on hemofiltration or hemofiltration dialysis, and number of days without antibiotics within 30 days;Proportion of patients with clinical response at 14 day;7-day total SOFA score and changes in individual organ SOFA scores;Inflammatory markers (PCT, IL-6);Daily total dose of vasopressors and number of days of vasopressors within 7 days for septic shock patients;All-cause mortality at 14 day;ICU length of stay;Total length of hospital stay; | — |
Countries
China
Contacts
Public ContactJiang Jinjiao
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Outcome results
None listed