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Clinical Study on the Diagnosis and Staging of Solid Tumours Including Brain Gliomas and Gastrointestinal Tumours Using PET Imaging with the Low-pH Insertion Compound Targeting FAP (FAPI-Var3)

Clinical study on the diagnosis, staging and metastasis detection of solid tumors based on PET imaging of low pH insertable compound (FAPI-Var3) targeting FAP

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111030
Enrollment
Unknown
Registered
2025-10-24
Start date
2025-10-27
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gliomas and solid tumours such as gastrointestinal tumours

Interventions

Index test:68Ga-FAPI-Var3 PET/CT

Sponsors

The First Affiliated Hospital of the People's Liberation Army Air Force Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old; 2. Patients pathologically diagnosed with gastrointestinal glioma and solid tumors in the gastrointestinal tract, as well as those scheduled for surgical resection or exploration (including primary or recurrent metastatic tumors); 3. As judged by a doctor, the expected survival period is more than 3 months; 4. Voluntarily sign the informed consent form; Willing and able to follow the research plan.

Exclusion criteria

Exclusion criteria: 1. Those with a history of allergy to 68Ga-FAPI-Var3 or its excipients; 2. People allergic to alcohol; 3. Those who cannot tolerate intravenous administration (such as those with a history of fainting at the sight of needles or blood); 4. Those who are not suitable for or unable to complete imaging examinations such as PET due to special reasons, including those with claustrophobia, radiophobia, etc. 5. Pregnant and lactating women; 6. Practitioners who need to be exposed to radioactive conditions for a long time; 7. Suffering from serious diseases of the heart, kidneys, lungs, blood vessels, nerves, mental system, etc., immune deficiency diseases and hepatitis/liver cirrhosis; 8. Have participated in other interventional clinical trials within one month prior to screening; 9. There are other circumstances that the researcher deems unsuitable for participation in this study

Design outcomes

Primary

MeasureTime frame
The maximum standardized uptake value;Average standardized uptake value;

Countries

China

Contacts

Public ContactWeidong Yang

the First Affiliated Hospital of the People's Liberation Army Air Force Military Medical University

2326604944@qq.com+86 29 8477 1048

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026