Depression
Conditions
Interventions
Sham stimulation group:NET treatment was performed, but the stimulation electricity was 0%
MECT treatment group:Stimulation amount converted to age ×80%
NET treatment group:Age ×40% stimulation amount
Sponsors
Nanning Fifth People's Hospital
Eligibility
Sex/Gender
All
Age
13 Years to 19 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were as follows: aged 13–19 years (based on WHO age stratification and the applicable age range of MECT for adolescents); meeting the DSM-5 diagnostic criteria for depression with melancholic features, with a total Hamilton Depression Rating Scale score indicating severe depression (>24 points); a total Dimensional Anhedonia Rating Scale (DARS) score <= 22; informed consent provided by a guardian; and no use of antidepressant medications within the two weeks prior to enrollment.
Exclusion criteria
Exclusion criteria: Exclusion criteria included: patients with a history of manic symptoms; those with depression induced by psychoactive substances or non-addictive substances; individuals with congenital mental disorders; and patients who failed to comply with prescribed medication or had incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD Rating Scale;DARS Rating Scale;BIS/BAS Rating Scale;rs-EEG; | — |
Secondary
| Measure | Time frame |
|---|---|
| NGASR Rating Scale;MocA cognitive level score;Levels of BDNF and inflammatory cytokines in serum; | — |
Countries
China
Contacts
Public ContactHuang Guangbiao
Nanning Fifth People's Hospital
Outcome results
None listed