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The influence of laparoscopic combined with flurbiprofen axetil and TAPB on the postoperative rehabilitation of elderly patients undergoing laparoscopic colorectal surgery

The influence of laparoscopic combined with flurbiprofen axetil and TAPB on the postoperative rehabilitation of elderly patients undergoing laparoscopic colorectal surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111026
Enrollment
Unknown
Registered
2025-10-23
Start date
2025-10-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Non exposure group: receiving traditional sufentanil combined with postoperative TAPB analgesia regimen:none
Exposure group: receiving a multimodal preemptive analgesia regimen of hydrocodone combined with flurbiprofen axetil and TAPB:none

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Aged 65 to 85; (2) ASA?-?; (3) Laparoscopic colorectal surgery under elective general anesthesia.

Exclusion criteria

Exclusion criteria: (1) Refuse to participate in this experiment; (2) Local infection at the puncture site of TAPB block; (3) Receive chemotherapy or radiotherapy before the operation; (4) Has undergone colorectal surgery; (5) Severe neurological and mental disorders: stroke combined with neurological dysfunction, Alzheimer's disease, schizophrenia, and other diseases for which postoperative follow-up cannot be completed; (6) Severe cardiovascular diseases: low cardiac output, heart failure, ejection fraction <40%, active coronary artery disease, symptomatic heart valve disease, symptomatic arrhythmia with or without a pacemaker and AICD placement; (7) Severe respiratory diseases: COPD requiring home oxygen therapy, severe pneumonia requiring hormone therapy, and other respiratory diseases requiring home oxygen therapy; (8) Patients with severe liver function abnormalities or liver failure classified asChild-Pugh grade c; (9) Severe renal insufficiency requiring renal replacement therapy.

Design outcomes

Primary

MeasureTime frame
Incidence of pogd;—

Secondary

MeasureTime frame
The time of the first postoperative exhaust;Tolerate the duration of oral feeding;Time for outdoor activities;Hospital stay;Visual Analogue Scale at 24 and 48 hours after the operation;The number of compressions of the analgesic pump;Complications of other organs;—

Countries

China

Contacts

Public ContactHuang Lining

The Second Hospital of Hebei Medical University

lininghuang@hotmail.com+86 158 0321 3730

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026