axial spondyloarthritis
Conditions
Interventions
axial spondyloarthritis group:N/A
healthy control group:N/A
Sponsors
General Hospital of Center Theater Command
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the axSpA Group 1. Aged 18-45 years, regardless of gender. 2. Meeting the 2023 expert consensus on the diagnosis and treatment of axial spondyloarthritis and the ASAS classification criteria. 3. Able to cooperate in completing all examination items. 4. Voluntarily participate in the study and sign the informed consent form. Inclusion Criteria for the Healthy Control Group 1. Age and gender matched with the disease group (+/-5 years). 2. No history of joint diseases. 3. Normal laboratory immune indicators. 4. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for the axSpA Group 1. Comorbid with other rheumatic immune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus). 2. History of central nervous system diseases (e.g., stroke, epilepsy, traumatic brain injury). 3. Contraindications for MRI examination (e.g., cardiac pacemaker, metal implants). 4. Severe hepatic or renal insufficiency. 5. Pregnant or lactating women. 6. Participation in other clinical studies within the past 3 months. Exclusion Criteria for the Healthy Control Group 1. History of chronic pain. 2. Having a first-degree relative with spondyloarthritis. 3. HLA-B27 positive. 4. The remaining criteria are the same as the exclusion criteria for the axSpA group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT value;T2 value;Mobility Score;cerebral functional paremeters;cerebral structural paremeters; | — |
Countries
China
Contacts
Public ContactHuang Wencai
General Hospital of Center Theater Command
Outcome results
None listed