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Application of VCAN-Functionalized BiNPs as Targeted Radiosensitizers in the Treatment of Recurrent Lacrimal Gland Adenoid Cystic Carcinoma

Application of VCAN-Functionalized BiNPs as Targeted Radiosensitizers in the Treatment of Recurrent Lacrimal Gland Adenoid Cystic Carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500111010
Enrollment
Unknown
Registered
2025-10-23
Start date
2025-10-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lacrimal Gland Adenoid Cystic Carcinoma

Interventions

Recurrent LGACC Group:None
Primary LGACC Group:None
LGP Group:None

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Inclusion Criteria for the LGACC Group: 1) Age between 18 and 60 years (inclusive), any gender. 2) Undergoing lacrimal gland tumor resection with pathological confirmation of lacrimal gland adenoid cystic carcinoma (LGACC), and availability of residual discarded lacrimal gland tissue after surgery. 3) Previously healthy, without history of inflammation or other diseases. 4) Complete clinical medical records available. (2) Inclusion Criteria for the Control Group (Lacrimal Gland Tissue): 1) Age and gender matched to the LGACC group. 2) Undergoing lacrimal gland surgery with pathological confirmation of lacrimal gland prolapse, and availability of residual discarded lacrimal gland tissue after surgery. 3) Previously healthy, without history of inflammation or other diseases. 4) Complete clinical medical records available.

Exclusion criteria

Exclusion criteria: 1) Diagnosed with other types of lacrimal gland tumors or having a history of other malignancies. 2) Presence of cardiac, renal, or hepatic dysfunction. 3) Concurrent immune system disorders.

Design outcomes

Primary

MeasureTime frame
Stability of the VCAN target site;

Secondary

MeasureTime frame
Success Rate of PDX Model Establishment;Histological Similarity;

Countries

China

Contacts

Public ContactQiuzi Zhong

Beijing Hospital

drzhongqiuzi@163.com+86 138 1042 8903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026