Acute respiratory distress syndrome
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age>= 18 years, regardless of gender; 2.Patients with ARDS meeting the diagnostic criteria of the "New Global Definition of Acute Respiratory Distress Syndrome" published by ESICM in 2023; 3.Receiving VV-ECMO support and having received invasive mechanical ventilation prior to the initiation of VV-ECMO; 4.The patient or legal representative has voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who have received a lung transplant or for whom VV-ECMO support was initiated for the purpose of bridge-to-lung transplantation therapy; 2.Patients with other severe diseases and a life expectancy of 15 hours per day): PaO2 55%). b) Patients requiring long-term home non-invasive ventilation support due to stable chronic respiratory failure: patients with severe chronic hypercapnia and a history of hospitalization due to acute respiratory failure, who still present with significant daytime persistent hypercapnia (PaCO2 >= 53 mmHg) 2 to 4 weeks after hospitalization for an acute exacerbation of COPD. 4.Complicated by cardiogenic shock requiring VA-ECMO support; 5.Patients who underwent ECMO cannulation at an outside hospital and for whom mechanical ventilation parameters prior to ECMO are unavailable; 6.Pregnant or lactating women; 7.Any condition that, in the investigator’s opinion, would increase the risk to the patient or interfere with the conduct of the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival rate at 60 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| ECMO weaning success rate;Duration of mechanical ventilation;ECMO complication rate;ECMO survival at 28 days, 3 months, and 6 months; | — |
Countries
China
Contacts
Public ContactYimin Li
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed