vascular cognitive impairment
Conditions
Interventions
5Hz stimulation group:conventional rehabilitation treatment + 5Hz VNMS stimulation in the left mastoid area
20Hz stimulation group :conventional rehabilitation treatment + 20Hz VNMS stimulation in the left mastoid area
Sponsors
The First College of Clinical Medical Science, China Three Gorges University;Yichang Central People’s Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Non-demented cognitive impairment after stroke (score on the Mini-Mental State Examination (MMSE): illiterate <=20, primary school literacy <=23, secondary school literacy <=27; Montreal Cognitive Assessment (MoCA) score <26) can cooperate with rehabilitation assessment and treatment. (Montreal Cognitive Assessment (MoCA) score <26) can co-operate with rehabilitation assessment and treatment; 2. Stable condition with no other medical history affecting cognitive function; 3. The duration of the disease is less than 6 months; 4. Age 55-80 years old; 5. Visual acuity and hearing ability to complete the relevant assessment; 6. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. cranial defects, with intracranial stents or pacemakers, etc. should not be treated with TBS; 2. accompanied by obvious dementia or mental disorder; 3. Combined with other related diseases that may affect the treatment, etc; 4. large cerebral infarction or haemorrhage, previous cerebrovascular disease or other diseases that affect cognitive function; 5. Combination of speech, visual and auditory impairment or communication difficulties that affect assessment and treatment; 6. Withdrawal from treatment midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment, MoCA;MRI (DTI-ALPS) examination;EEG;fNIRS examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Continuous performance task, CPT;Stroop-Color-and-Word-Test; N-back test;Event-related potential, ERP;BDNF; | — |
Countries
China
Contacts
Public ContactSun Liangwen
The First College of Clinical Medical Science, China Three Gorges University; Yichang Central People’s Hospital
Outcome results
None listed