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Clinical Study on the Impact of Alveolar Macrophage Senescence on Disease Severity in Patients with Idiopathic Pulmonary Fibrosis

Clinical Study on the Impact of Alveolar Macrophage Senescence on Disease Severity in Patients with Idiopathic Pulmonary Fibrosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110998
Enrollment
Unknown
Registered
2025-10-23
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

IPF Group (Disease Group):None
Other ILD Group (Control Group):None

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who were first seen at the Department of Respiratory and Critical Care Medicine of the First Affiliated Hospital of China Medical University and were diagnosed with IPF. 2. Patients who are first seen at the Department of Respiratory and Critical Care Medicine of the First Affiliated Hospital of China Medical University and are diagnosed with other ILDs (e.g., tuberculosis), according to the diagnostic criteria in Internal Medicine (10th edition). 3. No major heart disease, liver or kidney dysfunction or other influencing factors. 4. Understand the purpose of the study and sign the informed consent form. 5. 18 years old <= age <= 80 years old, gender is not limited.

Exclusion criteria

Exclusion criteria: 1.History of a major acute illness or major surgical procedure within the recent period. 2.Women who are pregnant or lactating. 3.End-stage malignant tumor or cachexia. 4.Patients with a history of severe psychological disorders or mental illness who are unable to comprehend the study content.

Design outcomes

Primary

MeasureTime frame
ß-galactosidase activity in peripheral blood and BALF;SASP in peripheral blood and BALF:IL-6?IL-8?TNF-a;Pulmonary Function Results;

Countries

China

Contacts

Public ContactWei Wang

The First Hospital of China Medical University

wwbycmu@126.com+86 24 8328 2999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026