Cardiorenal syndrome (CRS) refers to a clinical syndrome in which any organ in the heart or kidney experiences acute or chronic dysfunction, leading to acute or chronic dysfunction of another organ.
Conditions
Interventions
ARNI combined with vitamin D and hemodialysis treatment as the treatment group:None
ACEI/ARB, diuretics, hemodialysis, and other treatments as the control group:None
Sponsors
Xingtai People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. From December 2019 to February 2022, our hospital treated patients diagnosed with type IV cardiorenal syndrome.patient.
Exclusion criteria
Exclusion criteria: 1. Acute renal failure; 2. Malignant tumors; 3.Severe infections; 4. Initial blood pressure below 80/50 mmHg without the use of antihypertensive drugs; 5. Initial liver function exceeding the upper limit of normal by 2 times; 6. Initial blood potassium exceeding 5 5 mmol/L; 7. Age greater than 18 years old but less than 75 years old; 8. Unable to cooperate in completing the study or lost to follow-up due to reasons such as neurological and psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LVEF;creatinine;NT-proBNP;eGFR;urea nitrogen;Cystatin C; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine protein,;electrolyte;glucose;24hUTP;c-reactive protein;serum albumin; | — |
Countries
China
Contacts
Public ContactKong Lujiao
Xingtai People's Hospital
Outcome results
None listed