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Study on the Value of Serum S100A12 Protein Combined with PTX-3 and IL-17 in Evaluating the Severity and Prognosis of Adult Patients with Invasive Pulmonary Aspergillosis

Study on the Value of Serum S100A12 Protein Combined with PTX-3 and IL-17 in Evaluating the Severity and Prognosis of Adult Patients with Invasive Pulmonary Aspergillosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110977
Enrollment
Unknown
Registered
2025-10-23
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive Pulmonary Aspergillosis (IPA)

Interventions

Gold Standard:Diagnostic criteria from the '2020 Edition of the European Organization for Research on Cancer/Invasive Fungal Infections' and the 'Guidelines for the Diagnosis and Treatment of Invasive
Index test:Serum S100A12, Serum PTX-3

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients met the diagnostic criteria specified in the 2020 Edition of the Criteria by the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) and the Guidelines for the Diagnosis and Treatment of Invasive Fungal Infections in Critically Ill Patients.

Exclusion criteria

Exclusion criteria: 1. Patients under 18 years of age; 2. Patients who cannot tolerate bronchoscopy; 3.Patients with hematological malignancies, granulocytopenia, immunodeficiency, or those who have undergone organ transplantation; 4. Lost-to-follow-up patients; 5.Patients with incomplete data.

Design outcomes

Primary

MeasureTime frame
S100A12;PTX-3;Reach the number of positive samples;

Countries

China

Contacts

Public ContactXianming Fan

Affiliated Hospital of Southwest Medical University

fxm129@163.com+86 830 3165321

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026